INTESTINE Vol.16 No.4(1-4)

Theme Small colorectal cancer with high malignant potential
Title Endoscopic findings concerning malignancy potential of small invasive colorectal cancer
Publish Date 2012/07
Author Akiko Chino Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research
Author Yuko Hayashi Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research
Author Masahiro Igarashi Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research
Author Mizuka Imai Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research
Author Teruhito Kishihara Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research
Author Naoyuki Uragami Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research
Author Yoshiro Tamegai Division of Gastroenterology, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research
Author Yoshiya Fujimoto Digestive Surgery, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research
Author Masashi Ueno Digestive Surgery, Cancer Institute Ariake Hospital of Japanese foundation for Cancer Research
[ Summary ] Our study investigated 39 cases of submucosal invasive colorectal cancer 10 mm or less in size from 2005 to 2011. The endoscopic findings for malignancy potential were coexistent depressions with either protruding or sessile features or only depressed lesions. For that reason small lesions consisting of depressed lesions were considered to be nonpolypoid growths (NPG). Most were adenocarcinoma without being considered to be adenomas pathologically. This suggested they were de novo cancer. Those cases were very likely to develop deep invasion of the submucosa. Lymph node metastatic rates were also high. However, small polyps were difficult to observe in terms of features. Indigo-carmine dye spraying, with magnified NBI and magnified observation is useful in these cases.
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