INTESTINE Vol.16 No.4(1-2)

Theme Small colorectal cancer with high malignant potential
Title Endoscopic therapy concerns for invasive colorectal carcinoma treatment
Publish Date 2012/07
Author Hiro-o Yamano Department of Gastroenterology, Akita Red Cross Hospital
Author Kenjirou Yoshikawa Department of Gastroenterology, Akita Red Cross Hospital
Author Tomoaki Kimura Department of Gastroenterology, Akita Red Cross Hospital
Author Ryo Takagi Department of Gastroenterology, Akita Red Cross Hospital
Author Michiko Nakaoka Department of Gastroenterology, Akita Red Cross Hospital
Author Masayuki Miyajima Department of Gastroenterology, Akita Red Cross Hospital
Author Yusaku Tanaka Department of Gastroenterology, Akita Red Cross Hospital
Author Yoshihito Tanaka Department of Gastroenterology, Akita Red Cross Hospital
Author Kentaro Sato Department of Gastroenterology, Akita Red Cross Hospital
[ Summary ] To explore problems associated with endoscopic therapy for invasive colorectal carcinoma, 195 invasive colorectal carcinomial lesions, were examined in our center. The degree of histogenesis, diameter of tumors, macro-scopic form, degree of submucosal invasion, and selection of therapy were also investigated. As a result, large diameter lesions and those with deeper invasion and depressed lesions were chosen for surgical treatment. There was a tendency for endoscopic therapy to be chosen for small diameter lesions, protruded lesions, or flat lesions. However, we found that the ratio of massive invasion is high in small-depressed lesions. It was also observed that lymph vessel invasion rates were high with small protruded lesions. Therefore, we pointed out the possibility that these lesions could not be successfully treated with endoscopic therapy. After better understanding the clinicopathologic background of adaptations to pathological change, we proposed choosing endoscopic therapy for the proper conditions.
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