| Theme | Invasive colorectal cancer current status and practical issues of depth 1,000μm | |
|---|---|---|
| Title | Clinical issues for diagnostic strategies to measure depth of SM invasion 1,000μm, post EMR | |
| Publish Date | 2012/03 | |
| Author | Shoichi Saito | Dept. of Endoscopy, The Jikei University. School of Medicine |
| Author | Toshiki Nikami | Dept. of Internal Medicine, The Jikei University. School of Medicine, |
| Author | Naoto Tamai | Dept. of Endoscopy, The Jikei University. School of Medicine |
| Author | Tomohiko Ohya | Dept. of Endoscopy, The Jikei University. School of Medicine |
| Author | Hiroyuki Aihara | Dept. of Endoscopy, The Jikei University. School of Medicine |
| Author | Takeshi Suzuki | Dept. of Endoscopy, The Jikei University. School of Medicine |
| Author | Tomohiro Kato | Dept. of Endoscopy, The Jikei University. School of Medicine |
| Author | Hisao Tajiri | Dept. of Endoscopy / Dept. of Internal Medicine, The Jikei University. School of Medicine |
| Author | Masahiro Ikegami | Dept. of Pathology, The Jikei University. School of Medicine |
| [ Summary ] | We studied submucosal invasive cancers (SM-Ca.), as to whether it is possible to expand the indications for endoscopic treatment or not. During the period between 2003 and 2011, one hundred sixty SM-Ca. cases, excised endoscopically or surgically in our hospital were studied. The rate of lymph node (LN) metastasis was 10.6 % (17/160). Only 8.8 % (3/34) of the cases, performed required additional surgical resection after endoscopic treatment and revealed LN metastasis. The mean depth of invasion (4,127.5±1,183.5 μm) in SM-Ca. with LN metastasis was deeper compared to cases without LN metastasis. The minimum depth was 2,250μm in cases with LN metastasis. Of 41 cases (SM-S; 22, SM-M; 19) were followed-up without additional surgical resection and were observed closely (mean duration：36.9 month). In order to decrease the number of cases requirins further surgery after endoscopic treatment, the curable criterion for complete resection may need to include lesions ranging from 1,000μm in SM-Ca. | |