| Theme | Invasive colorectal cancer current status and practical issues of depth 1,000μm | |
|---|---|---|
| Title | Benefits and risks associated with cutoff values of invasion depth of 1,000 μm in patients with colorectal submucosal cancer | |
| Publish Date | 2012/03 | |
| Author | Kiyonori Kobayashi | Department of Gastroenterology, Kitasato University East Hospital |
| Author | Miyuki Mukae | Department of Gastroenterology, Kitasato University East Hospital |
| Author | Taishi Ogawa | Department of Gastroenterology, Kitasato University East Hospital |
| Author | Kaoru Yokoyama | Department of Gastroenterology, Kitasato University East Hospital |
| Author | Miwa Sada | Department of Gastroenterology, Kitasato University East Hospital |
| Author | Wasaburo Koizumi | Department of Gastroenterology, Kitasato University East Hospital |
| [ Summary ] | Colorectal submucosal cancer can be divided into two groups according to whether the depth of submucosal invasion is less than 1,000 μm or 1,000 μm or greater. The first is submucosal cancer with slight invasion and the second is submucosal cancer with massive invasion. The depth of submucosal invasion can be used as an index to preoperatively predict the risk of metastasis and recurrence in patients with submucosal tumors and is useful for selecting appropriate treatment strategies. Conventional endoscopy is primarily used to diagnose the depth of submucosal invasion. If it is difficult to make a diagnosis, endoscopic ultrasonography, evaluation of pit patterns through magnifying endoscopy, and image-enhancement techniques such as narrow-band imaging should be used. However, it is important to understand that the diagnostic accuracy of these techniques for determining-depth is limited. | |