INTESTINE Vol.16 No.2(4-1)

Theme Invasive colorectal cancer current status and practical issues of depth 1,000μm
Title Significance of and problems with using pSM depths of 1,000μm as diagnostic criteria
Publish Date 2012/03
Author Yoichi Ajioka Division of Molecular and Diagnostic Pathology, Graduate School of Medical and Dental Sciences, Niigata University
Author Hiroshi Kawachi Department of Human Pathology, Tokyo Medical and Dental University
[ Summary ] A pSM depth of 1,000μm is one histopathologic factor indicated in the JSCCR Guidelines (2005 and 2009) to determine treatment strategies for endoscopically resected pSM colorectal carcinoma (pSM CRC). A pSM depth less than 1,000μm is a significant factor to predict the curative potential of pSM CRC with endoscopic treatment. However, it must be noted that the overestimation of pSM depths of 1,000 μm or more as a factor to determine additional surgery after endoscopic resection may result in overtreatment of patients.
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