| Theme | Drug-induced gastrointestinal disorders | |
|---|---|---|
| Title | Gastrointestinal (GI) toxicity of chemotherapeutic drugs | |
| Publish Date | 2012/01 | |
| Author | Hironaga Satake | Department of Gastroenterology and GI oncology, National Cancer Center Hospital East |
| Author | Takayuki Yoshino | Department of Gastroenterology and GI oncology, National Cancer Center Hospital East |
| [ Summary ] | Gastrointestinal (GI) toxicity due to use of chemotherapeutic drugs is a common problem in cancer patients. Chemotherapy-induced diarrhea (CID) is one of the most commonly observed problems with these patients. CID can be debilitating and in some cases, life-threatening. Several molecularly targeted agents may lead to GI toxicity. Three types of colitis are described in relation to their association with chemotherapy : neutropenic enterocolitis, ischemic colitis, and C. difficile-associated colitis. | |