| Theme | Drug-induced gastrointestinal disorders | |
|---|---|---|
| Title | Causes of antibiotic-associated hemorrhagic colitis and future treatment | |
| Publish Date | 2012/01 | |
| Author | Wataru Ueda | Department of Gastroenterology, Osaka City Juso Hospital |
| Author | Koji Sano | Department of Gastroenterology, Osaka City General Hospital |
| Author | Masato Miyano | Department of Gastroenterology, Osaka City Juso Hospital |
| Author | Hiroko Ohba | Department of Gastroenterology, Osaka City Juso Hospital |
| Author | Tetsuya Aoki | Department of Gastroenterology, Osaka City Juso Hospital |
| Author | Osamu Kurai | Department of Gastroenterology, Osaka City Juso Hospital |
| Author | Kiyotaka Okawa | Department of Gastroenterology, Osaka City Juso Hospital |
| [ Summary ] | Antibiotic-associated hemorrhagic colitis (AAHC) usually occurres after antibiotic treatment. Patients having AAHC typically complain of acute abdominal pain and bloody stools. AAHC developes several days after taking of semisynthetic penicillin or other antibiotics. AAHC is segmental and predominantly located in the right or transverse colon. Colonoscopy shows edematous mucosa and erosion with submucosal hemorrhage. Although cause of AAHC is not known, however, recently K.oxytoca is the causative organism in at least some cases. | |