| Theme | Exploring problems of "villous tumor" | |
|---|---|---|
| Title | Histogenesis, growth patterns, and canceration of villous tumors of the large intestine | |
| Publish Date | 2011/11 | |
| Author | Hiroshi Tanabe | Department of Pathology, Fukuoka University, Chikushi Hospital |
| Author | Akinori Iwashita | Department of Pathology, Fukuoka University, Chikushi Hospital |
| Author | Seiji Haraoka | Department of Pathology, Fukuoka University, Chikushi Hospital |
| Author | Keisuke Ikeda | Department of Pathology, Fukuoka University, Chikushi Hospital |
| Author | Kaname Oshige | Department of Pathology, Fukuoka University, Chikushi Hospital |
| Author | Atsuko Ota | Department of Pathology, Fukuoka University, Chikushi Hospital |
| Author | Takao Kanemitsu | Department of Pathology, Fukuoka University, Chikushi Hospital |
| [ Summary ] | We studied 40 cases of villous tumors of the large intestine. Villous tumors were classified in four pathological types as follows ; (1) villous adenomas, (2) villous adenomas+adenocarcinomas, (3) villous adenocarcinomas+ villous/tubulovillous adenomas, (4) villous adenocarcinomas. We inferred from pathological features that villous tumors had two pathways toward histogenesis, growth patterns, and canceration. These pathways were ; (a) villous adenocarcinomas originating from de novo carcinomas and (b) adenocarcinomas without villous patterns and/or with villous adenomas originating from adenoma-carcinoma sequences. However, cases of villous adenocarcinoma in villous adenomas or with tubulovillous adenomas were reminiscent of villous adenocarcinomas originating from adenoma-carcinoma sequences. | |