INTESTINE Vol.15 No.3(2-12)

Theme Therapeutic strategy for ulcerative colitis ; from standard to up-to-date
Title Medical therapy for ulcerative colitis during pregnancy
Publish Date 2011/05
Author Reiko Kunisaki Inflammatory Bowel Disease Center, Yokohama City University Medical Center
Author Hisae Yamamoto Inflammatory Bowel Disease Center, Yokohama City University Medical Center
Author Hiroto Kinoshita Inflammatory Bowel Disease Center, Yokohama City University Medical Center
Author Reikei Matsuda Inflammatory Bowel Disease Center, Yokohama City University Medical Center
Author Machiko Nakatogawa Inflammatory Bowel Disease Center, Yokohama City University Medical Center
Author Shinsuke Suzuki Inflammatory Bowel Disease Center, Yokohama City University Medical Center
Author Hideaki Kimura Inflammatory Bowel Disease Center, Yokohama City University Medical Center
Author Shin Maeda Department of Gastroenterology, Yokohama City University Graduate School of Medicine
Author Mizuho Yamaguchi Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center
Author Mika Okuda Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center
Author Tsuneo Takahashi Perinatal Center for Maternity and Neonate, Yokohama City University Medical Center
[ Summary ] Ulcerative colitis does not seem to affect congenital abnormalities when the disease is inactive. However, active disease is a risk factor for preterm delivery and low birth weight. It seems the greatest risk to the mother and the fetus during pregnancy is active disease, and not the pharmacological agent used to treat it. Medical therapy for ulcerative colitis should generally continue during pregnancy and breast feeding, since the benefits of disease control outweigh the risks associated with medication.
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