INTESTINE Vol.14 No.5(10)

Theme Surgical therapy for Crohn's disease -- Essentials for physician
Title Cancer development in Crohn's disease patients and treatment strategies
Publish Date 2010/09
Author Hiroki Ikeuchi Department of Surgery, Hyogo College of Medicine / Inframmatory Bowel Disease Center, Hyogo College of Medicine
Author Motoi Uchino Department of Surgery, Hyogo College of Medicine / Inframmatory Bowel Disease Center, Hyogo College of Medicine
Author Hiroki Matsuoka Department of Surgery, Hyogo College of Medicine / Inframmatory Bowel Disease Center, Hyogo College of Medicine
Author Toshihiro Bando Department of Surgery, Hyogo College of Medicine / Inframmatory Bowel Disease Center, Hyogo College of Medicine
Author Hirofumi Sasaki Department of Surgery, Hyogo College of Medicine
Author Naohiro Tomita Department of Surgery, Hyogo College of Medicine
Author Yoshio Takesue Department of Infection Control and Prevention, Hyogo College of Medicine
Author Yoshihiro Fukuda Inframmatory Bowel Disease Center, Hyogo College of Medicine / General Medicine and Community Health Science, Hyogo College of Medicine
Author Takayuki Matsumoto Inframmatory Bowel Disease Center, Hyogo College of Medicine / Devision of Lower Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine
[ Summary ] The number of patients with Crohn's disease (CD) who develop cancer is increasing. In relation to the cases reported in Japan, this type of cancer is frequently associated with anorectal lesions. However, since it is difficult to make an early diagnosis, even by employing all presently available examination methods, the prognosis of affected individuals is poor. On the other hand, the quality of life for patients following a proctectomy has been reported to generally improve. Therefore, it is considered that rectal amputation may become a reasonable long-term option for patients with anorectal lesions, especially rectal stenosis.
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