| Theme | Bloody stools in non -- IBD intestinal disorders | |
|---|---|---|
| Title | Mucosal prolapse syndrome and cap polyposis | |
| Publish Date | 2010/01 | |
| Author | Taiji Akamatsu | Department of Endoscopy, Shinshu University Hospital |
| Author | Tadanobu Nagaya | Department of Internal Medicine, Gastroenterology, Shinshu University School of Medicine |
| Author | Naoshi Nakamura | Department of Internal Medicine, Marunouchi Hospital |
| [ Summary ] | Mucosal prolapse syndrome is thought to occurr due to chronic mechanical stimulation. It is often recognized in prolapsing colostomies, with colonic multiple diverticles, and in the rectum. Patients with mucosal prolapse syndrome in the rectum often strain during defecation, and have polypoid lesions and/or ulcerations in the anterior wall of the lower rectum. The etiology of cap polyposis is still unknown, however, some patients with cap polyposis have recently been cured through eradication therapy for Helicobacter pylori. Patients with cap polyposis usually complain of mucous bloody stools and/or mucoid diarrhea. Hypoproteinemia is often recognized in patients with multiple sessile polyps on the apices of the transverse mucosal fold of the rectum and the sigmoid colon. Previously, these both diseases were thought to have similar etiologies. However, there are many different points of comparison between mucosal prolapse syndrome of the rectum and cap polyposis. This is true not only in terms of clinical, endoscopic, and pathological features, but also in terms of clinical responses to treatments. On the basis of these findings, we believe that cap polyposis is not a mucosal prolapse syndrome, but a new clinical entity which may have a different pathogenesis. |
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