| Theme | Bloody stools in non -- IBD intestinal disorders | |
|---|---|---|
| Title | GI bleeding due to systemic disease | |
| Publish Date | 2010/01 | |
| Author | Yoshihito Nakagawa | Department of Gastroenterology, Fujita Health University School of Medicine |
| Author | Ichiro Hirata | Department of Gastroenterology, Fujita Health University School of Medicine |
| Author | Masami Iwata | Department of Gastroenterology, Fujita Health University School of Medicine |
| Author | Hiroshi Fujita | Department of Gastroenterology, Fujita Health University School of Medicine |
| [ Summary ] | In order to make a diagnosis of gastrointestinal (GI) bleeding due to systemic disease, it is important examine GI lesions as well as to gather the patient's clinical background. Lupus enteritis in systemic lupus erythematosus (SLE), which is caused by small vessel vasculitis, can be classified into two types : ischemic enteritis and multiple ulcers. GI bleeding is caused by the multiple ulcer type. Many polyarteritis nodosa (PN) patients suffer from GI bleeding or perforation, because PN is caused by small vessel vasculitis. The small intestine is the most common site of this bleeding or perforations. Churg-Strauss syndrome (allergic granulomatous angitis) is clinically characterized by bronchial asthma, eosinophilia and vasculitis. GI bleeding is observed in apploximally 30% of this angitis cases. Marked erythema is frequently observed in ulcer margins and erosions. Major indications of Henoch-Schönlein purpura are observed in the skin, articular, renal and abdominal regions. This desease endoscopically presents with diverse features, redness, ersion, ulcers, edema, purplish lesions. | |