| Theme | The newest approach to the small intestinal diseases | |
|---|---|---|
| Title | Intestinal Behçet's disease and simple ulcer | |
| Publish Date | 2009/09 | |
| Author | Kunihiko Aoyagi | Department of Gastroenterology, Fukuoka University Faculty of Medicine |
| Author | Yoshitaka Tomioka | Department of Gastroenterology, Fukuoka University Faculty of Medicine |
| [ Summary ] | Behçet's disease is a generalized syndrome characterized by four hallmark symptoms. In intestinal Behçet's disease, typical intestinal lesions are punched-out round or oval ulcers in the ileocecal region, while atypical lesions are multiple small ulcers throughout the gastrointestinal tract. Simple ulcer is defi ned as those having ileocecal punched-out ulcers similar to those observed with Behçet's disease without hallmark symptoms. These two conditions require medical, nutritional and surgical managements. However, these conditions frequently recur. Recently, anti-TNFα TNα therapy has been demonstrated to be effective in treatment of these conditions. | |