| Theme | Update in management of colitic cancer | |
|---|---|---|
| Title | Magnifying endoscopy for diagnosis of colorectal cancer and dysplasia -- associated with ulcerative colitis | |
| Publish Date | 2009/05 | |
| Author | Makoto Watanabe | Department of Gastroenterology, Fujita-Health University School of Medicine |
| Author | Naoko Maruyama | Department of Gastroenterology, Fujita-Health University School of Medicine |
| Author | Yoshio Kamiya | Department of Gastroenterology, Fujita-Health University School of Medicine |
| Author | Hiroshi Fujita | Department of Gastroenterology, Fujita-Health University School of Medicine |
| Author | Yoshihito Nakagawa | Department of Gastroenterology, Fujita-Health University School of Medicine |
| Author | Mitsuo Nagasaka | Department of Gastroenterology, Fujita-Health University School of Medicine |
| Author | Masami Iwata | Department of Gastroenterology, Fujita-Health University School of Medicine |
| Author | Kazuya Takahama | Department of Gastroenterology, Fujita-Health University School of Medicine |
| Author | Ichiro Hirata | Department of Gastroenterology, Fujita-Health University School of Medicine |
| [ Summary ] | Magnifying endoscopy has been used in the diagnosis of dysplasia and colitic cancer (CC) as well as sporadic neoplasia. We investigated the magnified endoscopic features of ulcerative colitis associated dysplasia and colitic cancer. Nineteen lesions associated with dysplasia and CC were included in this study. Magnified findings were classified by using Kudo's pit pattern criteria. Morphologically these lesions were classified into flat elevated, granular aggregated, sessile, protruded and flat types. Six lesions of flat elevated type and granular aggregated type were seen out of nineteen total lesions. The mucosal color of lesions was reddish in 63%. In magnifying endoscopic examination, type VI pit patterns was observed in 50% of CC cases and type IV pit patterns were identified in 33% of CC cases. Type IV pit patterns were seen in 85% of dysplasia cases. Type IV pit patterns were divided into villous patterns and branched patterns. NBI observation commonly showed type IIIA MC patterns with CC lesion and type II MC pattern with dysplasia. Type IV pit patterns were thought to be typical with both CC and dysplasia. Further studies are necessary to develope endoscopic diagnosis of CC and dysplasia. |
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