| Theme | Update in management of colitic cancer | |
|---|---|---|
| Title | Pit pattern diagnosis of ulcerative colitis associated dysplasia and cancer | |
| Publish Date | 2009/05 | |
| Author | Kazuo Ohtsuka | Digestive Disease Center, Showa University, Northern Hospital |
| Author | Kenichi Mizuno | Digestive Disease Center, Showa University, Northern Hospital |
| Author | Haruo Ikeda | Digestive Disease Center, Showa University, Northern Hospital |
| Author | Kunihiko Wakamura | Digestive Disease Center, Showa University, Northern Hospital |
| Author | Osamu Ito | Digestive Disease Center, Showa University, Northern Hospital |
| Author | Hiroshi Kashida | Digestive Disease Center, Showa University, Northern Hospital |
| Author | Yoshiki Wada | Digestive Disease Center, Showa University, Northern Hospital |
| Author | Shigeharu Hamatani | Department of Pathology, Showa University, Northern Hospital |
| Author | Shin-ei Kudo | Digestive Disease Center, Showa University, Northern Hospital |
| [ Summary ] | Magnifying colonoscopy is useful for detecting ulcerative colitis (UC) associated neoplasms. Mass, redness, abnormal vessels and stenosis indicate the existence of such tumors. Chromoendoscopy is helpful for detailed observation. Multicenter analysis indicated that 80% of such tumors exhibited type IIIL-like or IV-like pit patterns. Type IV-like pit patterns have branched, serrated and villous patterns. Those pit patterns are characterized by irregularity, various sizes, scattering and larger or fusion pits. Those characteristic patterns are termed neoplastic pit pattern of ulcerative colitis (NPUC). There are some problems ; One problem is that it is difficult to distinguish between sporadic cancer and UC associated neoplasms. Inflammatory mucosa and regenerative changes make it difficult to diagnose tumors. | |