INTESTINE Vol.13 No.2(2-2)

Theme Frontier of image diagnosis for colorectal carcinoma
Title Detectability of colorectal neoplastic lesions using narrow band imaging system
Publish Date 2009/03
Author Toshio Uraoka Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Author Yutaka Saito Division of Endoscopy, National Cancer Center Hospital
Author Reiji Higashi Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Author Shin Ishikawa Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Author Joichiro Horii Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Author Hideyuki Suzuki Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Author Jun Kato Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Author Takahisa Matsuda Division of Endoscopy, National Cancer Center Hospital
Author Yasushi Sano Gastrointestinal Center, Sano Hospital
Author Kazuhide Yamamoto Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
[ Summary ] Narrow band imaging (NBI) provides unique views especially of mucosal vascular networks and helps in the visualization of neoplasia by improving contrast. The detectability of colorectal neoplastic lesions using NBI has primarily been reported in western countries. However, these conclusions and opinions are controversial at present. Our prospective pilot study revealed that NBI colonoscopy improved the detection of fl at and diminutive lesions which tend to be easily missed, in the right side of the colon. It is important that endoscopic systems and specific image enhanced functions, such as surface structure and adaptive index of hemoglobin color enhancement settings be used. It is also important that examiners be sufficiently aware of fl at and depressed lesions to make definitive conclusions. In the future Japanese multi-center randomized controlled trials had been conducted to fully evaluate the efficacy of screening and surveillance colonoscopies.
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