| Theme | Frontier of image diagnosis for colorectal carcinoma | |
|---|---|---|
| Title | Effect of screening strategies for colorectal cancer with CT colonography | |
| Publish Date | 2009/03 | |
| Author | Koichi Nagata | Department of Radiology, Massachusetts General Hospital & Harvard Medical School |
| Author | Hiroyuki Yoshida | Department of Radiology, Massachusetts General Hospital & Harvard Medical School |
| [ Summary ] | Colorectal cancer is one of the most frequent malignancies in Japan, in wihch approximately 41,000 patients die of colorectal cancer in 2006. Although prevention of colorectal cancer by means of population screening is highly effective, screening rates are low and many barriers are present that need to be overcome in order to make a major global impact on colorectal cancer incidence and mortality. Computed tomographic colonography (CTC) is one of the colon cancer screening strategies that is known to be less expensive, less time-consuming, and better tolerated for patients than is optical colonoscopy. Recent large clinical CTC trials for screening of colorectal polyps demonstrated that CTC had a diagnostic performance similar to that of optical colonoscopy for detection of clinically significant polyps. Based on the success of these clinical trials, the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology now list CTC as a viable colorectal cancer screening in its new joint guideline. In this review, the authors discuss the essential aspects of screening strategies of colorectal polyps based on CTC, including the current techniques for patient preparation, data acquisition, image display and interpretation, as well as the CTC performance for screening. |
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