| Theme | Small invasive cancer of colon and rectum less than 10 mm | |
|---|---|---|
| Title | Pathological analysis of colorectal submucosal carcinoma less than 10 mm in diameter | |
| Publish Date | 2008/09 | |
| Author | Shigeharu Hamatani | Department of Pathology, Showa University Northern Yokohama Hospital |
| Author | Tomokazu Hisayuki | First Department of Pathology, Showa University |
| [ Summary ] | Sixty five colorectal submucosal carcinoma less than 10 mm were studied. These were divided into SM slight carcinoma (SM-s) (n = 26) and SM massive carcinoma (SM-m) (n = 39) according to the Kudo's classification. Type VN pit patterns was observed only in SM-m. Vessel invasion and lymph node metastasis, which are risk factors, were not seen in SM-s, but existed only in SM-m. The frequency of carcinomial appearance with high grade cytological atypia and disorder degree of gland structures was higher than in SM-s or SM-m. It is thought that radical treatment of SM-s may be carried out endoscopically. SM-m less than 10 mm has a high biological grade of malignancy, and is treatable with surgical procedures. However, the frequency of type VN pit pattern in SM-m less than 10 mm was only 36 %. It is considered possible that many examples of gland structures remain in SM-m which indicate the disorder degree of gland structures. In conclusion, it seems that it is difficult to identify examples which should chosen surgical procedures in cases of colorectal submucosal carcinoma less than 10 mm in conclusion. | |