| Theme | Considering of the endoscopic classification in development of early colorectal cancer | |
|---|---|---|
| Title | Endoscopic subclassiflcation of Is + IIc type early coloreetal cancer | |
| Publish Date | 2008/05 | |
| Author | Takeshi Nakajima | Division of Endoscopy, National Cancer Center Hospital |
| Author | Takahisa Matsuda | Division of Endoscopy, National Cancer Center Hospital |
| Author | Yutaka Saito | Division of Endoscopy, National Cancer Center Hospital |
| [ Summary ] | Is + IIc type early stage colorectal neoplasms can be divided into two types ; the NPG (non-polypoid growth) type and the PG (polypoid growth) type. The relation between the depth of invasion and the size of several types of early colorectal cancer for example, types Is + IIc, IIa + IIc and Is were examind. The incidence of submucosal invasion in Is + IIc lesions was relatively high compared to other types. This was especially, so in NPG-type Is + IIc colorectal cancer when it was over 11 mm in size. The rate of submucosal invasion in those cases reached 96.7 % (29 / 30). Even with smaller lesions (< 10 mm),the incidence of submucosal invasion with NPG-type Is + IIc lesions was 62.5 (5 / 8) whereas that for the Is type was only 0.4 % (6 / 1,393). In regard to PG-type Is + IIc lesions, larger than 11 mm in diameter, the rate of submucosal invasion was 67.9 % (19 / 28) . This suggests that some PG-type Is + IIc colorectal lesions may be intramucosal cancer. Therefore, proper treatment cannot be rendered without accurate endoscopic diagnosis, including magnifying examination. | |