| Theme | Mesenchymal neoplasms of the colon and rectum : excluding lymphoproliferative disorders | |
|---|---|---|
| Title | Clinical and pathologic features of colorectal granular cell tumor | |
| Publish Date | 2008/01 | |
| Author | Yasuhiro Takaki | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Akinori Iwashita | Department of Pathology, Fukuoka University Chikushi Hospital |
| Author | Sumio Tsuda | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Toshiyuki Matsui | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| Author | Kenshi Yao | Department of Gastroenterology, Fukuoka University Chikushi Hospital |
| [ Summary ] | Granular cell tumor (GCT) which can arise from various sites in the gastrointestinal tract is relatively rare disease. The most common site is the esophagus, followed by the large intestine and especially in the right side of the colon and the anorectum. In regard to endoscopic findings, most GCTs exhibit hard, yellowish submucosal nodules with smooth surfaces. In the large intestine, GCTs of less than 10 mm are found as a slighdy elevated submucosal nodules or have a hemispherical appearance, while GCTs larger than 10 mm are found as semipedunculated submucosal nodules. The characteristic molar tooth like appearance is seldom noted in the large intestine. Most GCTs in the GI tract are found as tumors of less than 2 cm in size and are diagnosed histologically as benign lesions. Therefore, most patients are safely treated with endoscopic treatments such as endoscopic polypectomy or endoscopic mucosal resection, which provide histological confirmation and treatment. | |