| Theme | Type V irregular pit in magnifying colonoscopy | |
|---|---|---|
| Title | Efficacy of magnifying colonoscopy in diagnosing early invasive colorectal cancer | |
| Publish Date | 2007/09 | |
| Author | Takahisa Matsuda | Division of Endoscopy, National Cancer Hospital |
| Author | Yutaka Saito | Division of Endoscopy, National Cancer Hospital |
| Author | Takeshi Nakajima | Division of Endoscopy, National Cancer Hospital |
| Author | Tsuyoshi Kikuchi | Division of Endoscopy, National Cancer Hospital |
| Author | Chizu Yokoi | Division of Endoscopy, National Cancer Hospital |
| Author | Shinsuke Kiriyama | Division of Endoscopy, National Cancer Hospital |
| Author | Haruhisa Suzuki | Division of Endoscopy, National Cancer Hospital |
| Author | Chika Kusano | Division of Endoscopy, National Cancer Hospital |
| Author | Yongmin Kim | Division of Endoscopy, National Cancer Hospital |
| Author | Takahiro Fujii | Takahiro Fujii Clinic |
| [ Summary ] | Many authors have reported on the efficacy of magnifying colonoscopy, not only to differentiate between non-neoplastic and neoplastic colorectal lesions, but also in diagnosing the invasion depth of early colorectal cancer. Magnifying colonoscopy identifies a typical pattern termed “invasive pattern”, which consists of irregular, distorted colonic gland crypts in a demarcated area. These patterns correspond to submucosal deep (SM-deep) invasive cancer, especially corresponding with totally destroyed muscularis mocosae. In this study the categories of highly irregular VI pit pattern and VI (invasive pattern are compared). The calculated sensitivity, specificity, and accuracy of highly irregular VI pit pattern were 92.7 % , 60.5 % , and 85.7 % respectively, differentiating SM superficial invasion (< 1,000 μm) from SM deep invasion (≥ 1,000 μm). On the other hand, the sensitivity, specificity, and accuracy of VI (invasive pattern) were 92.7 %, 71.1 %, and 88.0 % respectively. From this data, the category of highly irregular VI pit pattern is adequate to differentiate between SM superficial invasion and SM deep invasion. However, the classification of VI (invasive pattern) is more accurate than highly irregular VI pit pattern. |
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