INTESTINE Vol.11 No.2(5)

Theme NBI in colon and rectum
Title Morphological aspects of the angiogenesis in gastrointestinal tract
Publish Date 2007/03
Author Hidetsugu Yamagishi Department of Surgical and Molecular Pathology, Dokkyo Medical University
Author Yuko Ono Department of Surgical and Molecular Pathology, Dokkyo Medical University
Author Hirokazu Fukui Department of Surgical and Molecular Pathology, Dokkyo Medical University
Author Takahiro Fujimori Department of Surgical and Molecular Pathology, Dokkyo Medical University
Author Yasushi Sano Gastrointestinal Center, SANO Hospital
[ Summary ] Newly developed magnifying endoscopic and NBI (Narrow Band Imaging) systems have made it possible to observe pit patterns on the mucosal surface of the colon and vascular structurs in the colonic mucosa. With the NBI system, two specific frequencies of 415 and 540 nm are used. These frequencies can be absorbed in the hemoglobin of red blood cells and subsequently enhance vascular observation. NBI systems are useful to enhance images of vessels and enable us to distinguish tumor vessels from normal vessels in the colonic mucosa. With greater understanding of the morphological character of tumor vessels, we will be able to more precisely distinguish tumor tissues from other tissues.
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