INTESTINE Vol.10 No.3(6-1)

Theme Development of diagnosis of magnifying endoscopy
Title Magnifying colonoscopic observation for patients with ulcerative colitis
Publish Date 2006/05
Author Masaki Kunihiro Department of Internal Medicine, the Chugoku Electric Power Co., Inc. Chuden Hospital
Author Shinji Tanaka Department of Endoscopy, Hiroshima University Hospital
Author Yoshitaka Ueno Department of Endoscopy, Hiroshima University Hospital
Author Masaru Shimamoto Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University
Author Kyoko Yoshioka Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University
Author Tsuyoshi Hatakeyama Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University
Author Shiro Oka Department of Endoscopy, Hiroshima University Hospital
Author Kazuaki Chayama Department of Medicine and Molecular Science, Graduate School of Biomedical Sciences, Hiroshima University
[ Summary ] Colonoscopy plays an important role in the diagnosis of ulcerative colitis and the determination of disease activity. Standard colonoscopic findings, however, do not often agree with histologic findings. It was difficult to distinguish the remission stage from the active stage with standard colonoscopy in cases of Matts Grade 2 disease. However, the magnifying colonoscopes reflected histologic inflammation statas more accurately than did standard colonoscopic findings. Magnifying colonoscopy is useful for determining the degree of histologic change and for the prediction of periods of remission without biopsy in patients with ulcerative colitis.
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