| Theme | Development of diagnosis of magnifying endoscopy | |
|---|---|---|
| Title | The prediction of the depth of invasion by checking cellular atypia with Endo-Cytoscopy systems | |
| Publish Date | 2006/05 | |
| Author | Hirohito Sasaki | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Keita Sasajima | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Hiroshi Kashida | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Haruhiro Inoue | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Junichi Tanaka | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Kazuo Ohtsuka | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Shin-ei Kudo | Digestive Disease Center, Showa University Northern Yokohama Hospital |
| Author | Shigeharu Hamatani | Department of Pathology, Showa University Northern Yokohama Hospital |
| Author | Akira Shiokawa | Department of Pathology, Showa University Northern Yokohama Hospital |
| [ Summary ] | It can be said that magnifying colonoscopy has nearly been established as the primary tool in the diagnosis of early cololectal cancer. Magnified observation of intra papillary capillary loops (IPCL) in the esophagus is also considered. Histological findings of gastrointestinal lesions are made on the basis of light-microscopic examination of hematoxylin-eosin stained thin-slice specimens. Endo-Cytoscopy (E-C) systems, a type of novel "ultra-high" magnifying endoscopy, enable cellular level microscopic observation in vivo and can be applied clinically. They provide realtime histological images, in vivo, that correspond well with those of hematoxylin-eosin stained microscopic images. A study to clarity the usefulness of E-C in the diagnosis of colorectal neoplasms was conducted. Diagnostic accuracy was over 90 % in E-C compared with the final pathological diagnosis. We expect more accurate prediction of the depth of invasion by checking cellular atypia with E-C systems. |
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