| Theme | Development of diagnosis of magnifying endoscopy | |
|---|---|---|
| Title | The relationship between the subclassification of type VI pit patterns and superficial histological constructions in early colorectal cancer | |
| Publish Date | 2006/05 | |
| Author | Takeshi Tobaru | Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine |
| Author | Osamu Tsuruta | Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine |
| Author | Hiroshi Kawano | Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine |
| Author | Kenichi Yoshimori | Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine |
| Author | Michio Sata | Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine |
| [ Summary ] | Type V pit patterns, observed using magnifying endoscopy, are divided into VI and VN categories. The latter represents deeply invasive cancers, invading into the submucosa, whereas the former represents intramucosal cancer, which is slightly to deeply invasive of the submucosa. Therefore, we classified VI into two groups, studing our diagnostic abilities concerning invasion depth and the relationship between the subclassification of VI and superficial histological constructions. As a result, we obtained the following data : There was a high level of diagnostic ability and accuracy, as well as positive predictive values in cases where the carcinoma had invaded the submucosal layer more than sm2 or 1,000 μm. The subclassffication of type VI pits had a high correlation with the degeneration and disappearance of crypts, the state of muscularis mucosae and desmoplastic reaction. |
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