| Theme | Development of diagnosis of magnifying endoscopy | |
|---|---|---|
| Title | Efficacy of magnifying colonoscopy in diagnosing the depth of invasion of colorectal cancer | |
| Publish Date | 2006/05 | |
| Author | Takahisa Matsuda | Division of Endoscopy, National Cancer Center Hospital |
| Author | Yutaka Saito | Division of Endoscopy, National Cancer Center Hospital |
| Author | Toshio Uraoka | Division of Endoscopy, National Cancer Center Hospital |
| Author | Hisatomo Ikehara | Division of Endoscopy, National Cancer Center Hospital |
| Author | Yumi Mashimo | Division of Endoscopy, National Cancer Center Hospital |
| Author | Tsuyoshi Kikuchi | Division of Endoscopy, National Cancer Center Hospital |
| Author | Naoko Okabe | Division of Endoscopy, National Cancer Center Hospital |
| Author | Kohei Takizawa | Division of Endoscopy, National Cancer Center Hospital |
| Author | Yoko Tateishi | Division of Endoscopy, National Cancer Center Hospital |
| Author | Daizo Saito | Division of Endoscopy, National Cancer Center Hospital |
| Author | Yasushi Sano | Division of Digestive Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East |
| Author | Takahiro Fujii | Takahiro Fujii Clinic |
| [ Summary ] | It has been said that is possible to estimate the depth of invasion of neoplastic colorectal lesions using magnifying colonoscopy in order to decide the correct treatment. Magnifying colonoscopy identifies a typical pattern, termed “invasive pattern”, which consists of irregular, distorted colonic gland crypts in a demarcated area. This type of pattern corresponds to submucosal deep (sm2 - 3) invasive cancer. It especially corresponds with completely destroyed muscularis mocosae. The calculated sensitivity, specificity, and accuracy were 85.6 %, 99.4 %, and 98.8 % respectively to differentiated intramucosal or sm1 invasion (<1,000 μm) from sm2 - 3 invasion (≥1,000 μm). Of the lesions which were endoscopically diagnosed as “invasive pattern”, a high percentage had invasive cancer, especially sm2 - 3 invasive cancer, where surgical resection is undoubtedly the proper treatment. | |