| Theme | Reconsideration of Gastritis | |
|---|---|---|
| Title | Infectious Gastritis Caused by Agents Other than Helicobacter pylori | |
| Publish Date | 2019/12 | |
| Author | Koji Ikegami | Division of Gastroenterology, Matsuyama Red‒cross Hospital |
| Author | Koichi Kurahara | Division of Gastroenterology, Matsuyama Red‒cross Hospital |
| Author | Shuji Kochi | Department of Internal Medicine, Chihaya Hospital |
| Author | Hiroki Yaita | Division of Gastroenterology, Matsuyama Red‒cross Hospital |
| Author | Shohei Uraoka | Division of Gastroenterology, Matsuyama Red‒cross Hospital |
| Author | Yumi Ohshiro | 3Department of Pathology, Matsuyama Red‒cross Hospital |
| [ Summary ] | Infectious gastritis caused by agents other than Helicobacter pylori is rare and is diagnostically challenging. Gastric syphilis is characterized by ulcerative lesions, which frequently occur in the gastric antrum, as well as disc‒like elevated lesions with a central white depression observed in the gastric body to the fornix. Gastric syphilis may increase in the future because an increasing number of Japanese patients are being diagnosed with primary syphilis. Gastric tuberculosis often presents with ulcerative lesions that extend between the gastric antrum and the lesser curvature of the gastric body, although this condition may show a varied presentation. Biopsy, culture, polymerase chain reaction, and interferon‒Γ release assay testing is warranted in cases with a high index of clinical suspicion. Cytomegalovirus gastritis, which often develops as an opportunistic infection presents with multiple punched‒out or map‒like ulcers that frequently extend between the angulus of the stomach and the antrum, with redness that appears bordered. Gastric candidiasis presents with multiple ulcers with thick belag and ulcer mound, or nodular lesions, often without esophageal candidiasis. Accurate identification of these characteristics enables early diagnosis and prompt treatment following appropriate biopsies and other confirmatory tests. | |