Clinical Gastroenterology Vol.34 No.13(6)

Theme Reconsideration of Gastritis
Title Clinicopathological and Endoscopic Characteristics of Type A Gastritis and Differences Between Type A and B Gastritis
Publish Date 2019/12
Author Shuichi Terao Kakogawa Central City Hospital
Author Shiho Suzuki Kakogawa Central City Hospital
Author Hidenobu Watanabe PCL Japan
[ Summary ] The clinical features of type A gastritis include achlorhydria, hypergastrinemia, pernicious anemia, significantly low pepsinogen (PG) I levels, a low PG I/II ratio, iron deficiency anemia, and concomitant autoimmune diseases.
Prominent pathological differences between type A and type B gastritis contribute to the differences in endoscopic appearance characterizing the two entities. Type A gastritis is endoscopically characterized by pan‒atrophy of the corpus, various shapes of the remnant oxyntic mucosa, scattered minute whitish protrusions, sticky adherent dense mucus, and diversity in endoscopic appearance of the antrum. Type B gastritis is endoscopically characterized by diffuse redness and mucosal swelling in non‒atrophic areas and discolored mucosa with vascular visibility in atrophic areas; these areas are demarcated by an atrophic border showing various degrees of mucosal atrophy.
Detailed examination is essential to diagnose concomitant type A and B gastritis.
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