Clinical Gastroenterology Vol.34 No.12(2-9)

Theme IPMN/Pancreatic Cyst as an Increasing Common Disease -- Current Status and Issues
Title How to Manage Small Pancreatic Cysts or Small IPMN
Publish Date 2019/11
Author Naoki Sasahira Department of Hepato‒Biliary‒Pancreatic Medicine, The Cancer Institute Hospital of Japanese Foundation for Cancer Research
Author Tsuyoshi Takeda Department of Hepato‒Biliary‒Pancreatic Medicine, The Cancer Institute Hospital of Japanese Foundation for Cancer Research
Author Ryo Kanata Department of Hepato‒Biliary‒Pancreatic Medicine, The Cancer Institute Hospital of Japanese Foundation for Cancer Research
Author Masato Matsuyama Department of Hepato‒Biliary‒Pancreatic Medicine, The Cancer Institute Hospital of Japanese Foundation for Cancer Research
Author Takashi Sasaki Department of Hepato‒Biliary‒Pancreatic Medicine, The Cancer Institute Hospital of Japanese Foundation for Cancer Research
Author Masato Ozaka Department of Hepato‒Biliary‒Pancreatic Medicine, The Cancer Institute Hospital of Japanese Foundation for Cancer Research
[ Summary ] Incidental small pancreatic cysts include branch duct IPMN in its early stage. There are two types of IPMN‒related pancreatic cancer (PC); PC derived from IPMN and PC concomitant with IPMN. The latter one can develop not only from advanced IPMN, but also from early stage of IPMN. Although the annual rate of the cancer incidence from IPMN is estimated as high as 0.5 %, the T1‒stage cancer progresses to T4 stage in just over 1 year. Thus, routine follow‒up of IPMN in its early stage should be performed twice a year by ultrasonography, dynamic CT scan, MR cholangiopancreatography, or endoscopic ultrasound. We should pay attention to the ductal change as well as the size or mucinous nodule of IPMN on those imaging study to find small PC concomitant with IPMN.
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