Clinical Gastroenterology Vol.34 No.12(2-4)

Theme IPMN/Pancreatic Cyst as an Increasing Common Disease -- Current Status and Issues
Title Role of EUS in the Diagnosis of Malignant IPMN and IPMN Concomitant Pancreatic Ductal Adenocarcinoma
Publish Date 2019/11
Author Ken Kamata Department of Gastroenterology and Hepatology, Kindai University Hospital
Author Akane Hara Center for General Medical Education and Clinical Training, Kindai University Hospital
Author Kentaro Yamao Department of Gastroenterology and Hepatology, Kindai University Hospital
Author Mamoru Takenaka Department of Gastroenterology and Hepatology, Kindai University Hospital
Author Masatoshi Kudo Department of Gastroenterology and Hepatology, Kindai University Hospital
[ Summary ] It is important to diagnose the presence or absence of mural nodules in cysts in order to distinguish between benign and malignant IPMN. The international consensus Fukuoka guidelines for the management of IPMN of the pancreas were revised in 2017, and the criteria for mural nodules was newly established with respect to contrast effects and nodule height. In recent years, several studies have focused on the evaluation of mural nodules by contrast‒enhanced harmonic EUS (CH‒EUS) for the purpose of discriminating between benign and malignant IPMN. CH‒EUS can be a useful diagnostic method for differentiating mural nodules and mucous masses and for diagnosing benign and malignant IPMN. There are many reports regarding the risk of developing IPMN concomitant pancreatic ductal adenocarcinoma (PDAC) is high in cases with IPMN mainly in Japan. In our case, EUS and CH‒EUS were useful for early detection of IPMN concomitant PDAC which may occur in IPMN follow‒up cases and remnant pancreas follow‒up cases after surgical resection of IPMN.
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