| Theme | Surveillance after Treatment for Colorectal Tumors | |
|---|---|---|
| Title | Characteristics of Interval Colorectal Cancer | |
| Publish Date | 2018/07 | |
| Author | Yoshio Kusaba | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| Author | Osamu Tsuruta | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| Author | Tsutomu Nagata | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| Author | Hidenori Tokuyasu | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| Author | Akihiro Ouchi | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| Author | Michita Mukasa | Division of Gastroenterology, Division of GI Endoscopy, Department of Medicine, Kurume University School of Medicine / Division of Endoscopy, Kurume University School of Medicine |
| [ Summary ] | Interval colorectal cancer is defined as an invasive cancer that is diagnosed using another test within the next fiscal year after a negative immunochemical fecal occult blood test (iFOBT) result. Any cancers that are diagnosed within 1 year of a negative screening result or after a positive screening result, wherein further investigation yielded a negative result or was refused, are classified as interval cancers. Few studies have reported on interval colorectal cancer in individuals undergoing screening based on iFOBT. We investigated the characteristics of interval colorectal cancer among participants of an iFOBT screening program. Interval colorectal cancer showed characteristic features with respect to sex, age, location, and stage. Compared with positive cancers, interval cancers were significantly more likely to be of higher stage and involve the cecum. A higher proportion of patients with metastatic lesions were present in the interval group than in the positive cancer group. Annual screening is effective for reducing the incidence of interval cancers, and interventions to promote continuous participation in screenings are required. For valid comparison among various areas or facilities, it is necessary to unify the operational definition and analytical methods of interval cancer. |
|