Clinical Gastroenterology Vol.33 No.4(3)

Theme Chronic Constipation : A New Classification, Pathophysiology, Diagnosis, Treatment
Title Pathophysiology of Chronic Constipation
Publish Date 2018/04
Author Kenji Kanoshima Department of Gastroenterology and Hepatology, Yokohama City University Hospital
Author Hidenori Ohkubo Department of Gastroenterology and Hepatology, Yokohama City University Hospital
Author Atsushi Nakajima Department of Gastroenterology and Hepatology, Yokohama City University Hospital
[ Summary ] Chronic constipation is classified into these categories : organic defection disorder, normal transit constipation (NTC), slow transit constipation (STC), and outlet delay/outlet obstruction (OD). As potential causes of chronic constipation, small intestine movement disorder, colon movement disorder, and rectal‒anal movement disorder may not be clear‒cut and could overlap each other to form the overall disorder of chronic constipation.
Although the state of each disease was unknown for a long time, new knowledge has been obtained by the gastrointestinal motility examination developed recently, and a detailed understanding of each pathological condition is expected in the future.
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