Clinical Gastroenterology Vol.33 No.3(5-4)

Theme GERD in Clinical Practice 2018 -- Current Status and Issues
Title Gastroesophageal Reflux Disease and Respiratory Diseases
Publish Date 2018/03
Author Koki Kawanishi Second Department of Internal Medicine, Wakayama Medical University
Author Takao Maekita Second Department of Internal Medicine, Wakayama Medical University
Author Jun Kato Second Department of Internal Medicine, Wakayama Medical University
Author Mikitaka Iguchi Second Department of Internal Medicine, Wakayama Medical University
Author Takeichi Yoshida Second Department of Internal Medicine, Wakayama Medical University
Author Masayuki Kitano Second Department of Internal Medicine, Wakayama Medical University
[ Summary ] Reportedly, gastroesophageal reflux can induce and aggravate a number of respiratory diseases including asthma, idiopathic pulmonary fibrosis, chronic obstructive pulmonary disease, cystic fibrosis, and obstructive sleep apnea syndrome. In contrast, a few reports have shown that respiratory disease can induce gastroesophageal reflux. Therefore, the relationship between these disease entities remains unclear. Nonetheless, proton pump inhibitors are occasionally prescribed as auxiliary agents for the treatment of respiratory diseases. In light of the evidence presently available, this strategy can be justified only for the management of asthma.
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