| Theme | NASH 2018 | |
|---|---|---|
| Title | Diagnostic Imaging of NASH/NAFLD | |
| Publish Date | 2018/01 | |
| Author | Natsuko Kobayashi | Department of Ultrasound Center, Hyogo College of Medicine |
| Author | Hiroko Iijima | Department of Ultrasound Center, Hyogo College of Medicine |
| Author | Masahiro Yoshida | Department of Ultrasound Center, Hyogo College of Medicine |
| Author | Takashi Nishimura | Department of Ultrasound Center, Hyogo College of Medicine |
| Author | Shuhei Nishiguchi | Department of Internal Medicine, Division of Hepatobiliary and Pancreatic Disease, Hyogo College of Medicine |
| Author | Seiichi Hirota | Department of Surgical Pathology, Hyogo College of Medicine |
| Author | Reiichiro Kondo | Department of Diagnostic Pathology, Kurume University Hospital |
| Author | Hirohisa Yano | Department of Diagnostic Pathology, Kurume University Hospital |
| Author | Masayoshi Kage | Department of Diagnostic Pathology, Kurume University Hospital |
| [ Summary ] | Liver biopsy is the gold standard for the diagnosis of nonalcoholic steatohepatitis (NASH), but it is difficult to perform on all nonalcoholic fatty liver disease (NAFLD) patients owing to its invasiveness. Therefore, it is necessary to develop non-invasive imaging methods for the diagnosis of NASH to replace liver biopsy. Ultrasound is the most widely used noninvasive modality for NAFLD screening. Recently, ultrasound has been used to quantitatively evaluate liver fat on the basis of the fat-attenuation feature. In addition, elastography using ultrasound and magnetic resonance imaging as non-invasive methods for the evaluation of liver fibrosis has recently been developed, and its utility for diagnosis of NASH has been reported. | |