Clinical Gastroenterology Vol.32 No.4(6)

Theme Towards Standardization of ESD Procedures
Title Endoscopic Closure of Mucosal Defects after Endoscopic Submucosal Dissection
Publish Date 2017/04
Author Teppei Akimoto Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine
Author Osamu Goto Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine
Author Motoki Sasaki Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine
Author Toshihiro Nishizawa Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine
Author Naohisa Yahagi Division of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine
[ Summary ] Endoscopic submucosal dissection (ESD) is widely accepted in Japan. However, postoperative bleeding and delayed perforation after ESD have persisted. As mucosal closure after ESD may prevent these postoperative adverse events, several techniques regarding endoscopic mucosal closure have been introduced, which include closure using endoscopic clips only, closure technique using hemoclips and supplement devices, and specially designed endoscopic suturing devices. As the number of patients taking antithrombotic agents increase, establishment of an easy and secure closure method and accumulation of evidences regarding efficacy of mucosal closure will be desired.
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