| Theme | The Gastrointestinal Tract and Appetite Control : Essential Clinical Knowledge | |
|---|---|---|
| Title | Involvement of Nesfatin—1 in the Regulation of Appetite and Gastrointestinal Function | |
| Publish Date | 2016/08 | |
| Author | Shiko Kuribayashi | Department of Gastroenterology and Hepatology, Gunma University Hospital |
| Author | Motoyasu Kusano | Department of Gastroenterology and Hepatology, Gunma University Hospital |
| Author | Masatomo Mori | Metabolic and Obese Research Institute |
| [ Summary ] | Considerable attention has been paid to the relationship between obesity and the development of gastrointestinal (GI) dysfunctions. We identified a novel endogenous molecule, nesfatin‒1, expressed in both the brain and adipocytes, that functions as a satiety factor and suppresses adipogenesis. Nesfatin‒1, which is also localized in the GI tract, might contribute to the development of some GI tract disorders. | |