| Theme | For Adequate Operation of Colorectal ESD/EMR Guidelines | |
|---|---|---|
| Title | Correct Operation of the Colorectal ESD/EMR Guidelines : Point as Viewed from the Pathology | |
| Publish Date | 2016/01 | |
| Author | Shigeharu Hamatani | Division of Pathology Clinical Service, Katsushika Medical Center Hospital, Jikei University School of Medicine |
| Author | Masahiro Ikegami | Department of Pathology, Jikei University School of Medicine |
| Author | Shinichi Hirooka | Division of Pathology Clinical Service, Jikei University School of Medicine |
| Author | Daisuke Aizawa | Department of Pathology, Jikei University School of Medicine |
| Author | Takehiro Mitsuishi | Department of Gastroenterology and Hepatology, Jikei University School of Medicine |
| Author | Shoichi Saito | Division of Endoscopy, Jikei University School of Medicine |
| [ Summary ] | The curability of colorectal ESD/EMR specimens is determined histopathologically. Proper handling and assessment of various histological factors is important for making decisions on treatment options. In this paper, the extension of specimen and its rapid fixation, specifically explained as the main points of macroscopic observation and cut‒out I mentioned the notes. Furthermore, I outline the important histological factors associated with radical determination, histological type, depth of invasion, invasion degree, vascular invasion, and tumor budding and margins. I also discuss the usefulness of special methods of immunostaining. In order to determine the curability of colorectal ESD/EMR specimens appropriately, it seems necessary to identify the absolute risk and safety factors for lymph node metastasis. |
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