| [ Summary ] |
Cirrhosis is an end stage diffuse liver disease caused by many factors. Histologically, cirrhosis is characterized by nodularity and fibrosis, including round nodules surrounded by fiberous septa. Diagnosis of cirrhosis is based on histological findings obtained from biopsy specimens, or on laparoscopic findings of irregular liver surfaces. However, in practical medicine, cirrhosis is usually best determined by a combination of clinical findings, laboratory date, and imaging studies. Etiology, functional reserves, and complications should also be evaluated. With progress of the disease, not only the liver is injured, but also many other parts of the body would be affected. In addition, cirrhosis presentsa high risk of hepatocellular carcinoma (HCC) development. In the cirrhotic liver, precise diagnosis of functional reserves is needed for proper clinical management or treatment of complications. The Child-Pugh score is the most common method to do so. CLIP scores or JIS scores are indicated in cases with HCC. The MELD score is used in most critical cases. |