| Theme | Best Available Managements of Helicobacter pylori Gastritis | |
|---|---|---|
| Title | Diagnosis and Eradication Therapy for Helicobacter pylori Infection in Children | |
| Publish Date | 2014/03 | |
| Author | Masumi Okuda | Department of General Medicine and Community Health Science, Hyogo College of Medicine / Department of Pediatrics, Sasayama Medical Center, Hyogo College of Medicine |
| Author | Kyoko Ohsaki | Department of General Medicine and Community Health Science, Hyogo College of Medicine / Department of Pediatrics, Sasayama Medical Center, Hyogo College of Medicine |
| Author | Tomohiro Tachikawa | Department of General Medicine and Community Health Science, Hyogo College of Medicine / Department of Pediatrics, Sasayama Medical Center, Hyogo College of Medicine |
| Author | Kohei Maekawa | Department of General Medicine and Community Health Science, Hyogo College of Medicine / Department of Pediatrics, Sasayama Medical Center, Hyogo College of Medicine |
| Author | Yoshihiro Fukuda | Department of General Medicine and Community Health Science, Hyogo College of Medicine |
| [ Summary ] | In children, Helicobacter pylori infection is associated with gastritis, peptic ulcers and iron deficiency anemia. Noninvasive diagnostic methods include the urea breath test and stool antigen tests. These are the most commonly performed tests. However, administration of antibiotics and PPIs often produces effects on test results. Serum antibody tests are not recommended because they have low sensitivity when used in younger children and do not indicate infectious conditions. Therefore, those tests must be used in combination with other methods. Because the resistance rate to clarithromycin has risen to over 40 % in Japanese children, susceptibility tests are needed before therapy. | |