| Theme | Determination of Gastric Cancer Risk -- Current Conditions and Issues | |
|---|---|---|
| Title | Identification of Patients with Previous Helicobacter pylori Infection | |
| Publish Date | 2013/07 | |
| Author | Mitsugi Yasuda | Federation of National Public Service Personnel Mutual Aid Association Takamatsu Hospital |
| Author | Tsuyoshi Maeta | Federation of National Public Service Personnel Mutual Aid Association Takamatsu Hospital |
| Author | Makoto Oryu | Federation of National Public Service Personnel Mutual Aid Association Takamatsu Hospital |
| Author | Akira Yamanoi | Kagawa Prefectural Cancer Detection Center |
| [ Summary ] | Methods to identify members of our group A who were previously infected with Helicobacter pylori (H. pylori) are discussed. Serum analysis was the most accurate method to identify individuals who were previously infected, based on H. pylori-specific IgG antibody titers of 3 U/ml or higher or PGⅠ< 32 ng/ml. Despite signs of atrophic changes, gastroscopy revealed no diffuse redness in the gastric mucosa, edema, swollen gastric folds, or exudates. These indications were crucial to develop diagnoses. X-ray images of the stomach, featured thin gastric folds which appeared irregular and interrupted, as well as displaying slight unevenness of the gastric mucosa. Few signs of gastric areas suggesting that an individual had previously been infected with H. pylori were observed. A standardized system to screen for stomach cancer to properly care for individuals who were previously infected with H. pylori should be developed as soon as possible. | |