| Theme | NASH -- Pathogenesis and Treatment | |
|---|---|---|
| Title | Utility of and Problems with NASH Animal Models | |
| Publish Date | 2013/04 | |
| Author | Goshi Shiota | Department of Genetic Medicine and Regenerative Therapeutics, Graduate School of Medicine, Tottori University |
| [ Summary ] | In this review, we discuss the importance of animal models as tools for NASH research. The characteristics, utilities and problems with 14 mouse NAFLD models are described. Of the 14 mouse models which were reported on to this time, none are the hoped for models for human NAFLD treatment. These models may prove to be important for the study of the pathophysiology of NASH if they can be used for future research. | |