Clinical Gastroenterology Vol.28 No.2(3-7-2)

Theme Treatment of Gastrointestinal Disorders Using Traditional Japanese Herbal Medicine : Present Status and Future Prospects
Title Improvement of General Conditions and Attenuation of Side Effects of Chemotherapy by Kampo in Patients with Gastrointestinal Cancers
Publish Date 2013/02
Author Yoshiharu Motoo Department of Medical Oncology, Kanazawa Medical University
[ Summary ] In order to improve general conditions for cancer patients, hochuekkito and juzentaihoto are often used, and anti-inflammatory formulas are recommended for patients with tumor fevers. Attenuation of side effects from chemotherapy, is being evaluated in terms of basic and clinical evidence concerning the effects of rikkunshito on chemotherapy-induced anorexia. Oxaliplatin-induced peripheral neuropathy is difficult to prevent. Although the effects of goshajinkigan have been examined in several clinical trials, there is no concrete evidence of its efficacy. For hematotoxicity, juzentaihoto, kamikihito, and ninjinyoeito have been tested, and hangeshashinto seems to be useful for treatment of irinotecan-induced diarrhea and chemotherapy-induced oral mucositis. In order to complete a standard treatment, Kampo has been widely introduced to clinical practice, although there are few clinical trials of high quality concerning its efficacy.
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