Clinical Gastroenterology Vol.28 No.13(8)

Theme Diagnostic and Interventional EUS -- Present Status and Future Perspectives
Title EUS-guided Gallbladder Drainage and Its Application of NOTES
Publish Date 2013/12
Author Takao Itoi Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Atsushi Sohuni Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Fumihide Itokawa Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Toshio Kurihara Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Kentaro Ishii Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Shujiro Tsuji Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Takayoshi Tsuchiya Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Nobuhito Ikeuchi Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Junko Umeda Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Reina Tanaka Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Ryosuke Tonotsuka Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Miki Honjo Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Shuntaro Mukai Department of Gastroenterology and Hepatology, Tokyo Medical University
Author Fuminori Moriyasu Department of Gastroenterology and Hepatology, Tokyo Medical University
[ Summary ] In general, early or emergency cholecystectomy is considered the gold standard for treatment for acute cholecystitis. Although cholecystectomy is relatively safe, the mortality rates for cholecystectomies in patients at high risk due to comorbid conditions is high. Therefore, high-risk patients have been treated with temporary therapy regimens to percutaneously decompress the gallbladder, e. g. percutaneous transhepatic gallbladder drainage (PTGBD) or aspiration (PTGBA). Apart from percutaneous transhepatic therapy, several endoscopists have reported that endoscopic transpapillary naso-gallbladder drainage or gallbladder stenting can also be used as palliative therapy for acute cholecystitis. In 2007, endoscopic ultrasosographyguided gallbladder drainage (EUS-GBD), which is divided into the categories of EUS-guided naso-gallbladder drainage and EUS-guided gallbladder drainage, was reported to be a viable alternative gallbladder drainage technique. Since that time, a number of studies of this technique have been conducted. Although the technical and clinical success of EUS-guided gallbladder drainage is almost 100 %, the complication rates range from 11 % to 33 %. Thus, until methodologies and dedicated devices are developed, we should be wary of potentially serious complications.
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