Clinical Gastroenterology Vol.28 No.12(5)

Theme Obesity Related Digestive Diseases
Title Obesity and Colorectal Cancer
Publish Date 2013/11
Author Munehiro Kugai Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science / Department of Gastroenterology and Hepatology, Maizuru Medical Center
Author Naohisa Yoshida Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science / Department of Gastroenterology and Hepatology, Nara City Hospital
Author Yutaka Inada Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science
Author Nobuaki Yagi Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science
Author Yuji Naito Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science
Author Kazuyuki Kanemasa Department of Gastroenterology and Hepatology, Nara City Hospital
Author Naoki Wakabayashi Department of Gastroenterology, Otsu Municipal Hospital
Author Akio Yanagisawa Department of Surgical Pathology, Kyoto Prefectural University of Medicine
Author Yoshito Itoh Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science
[ Summary ] It has been found in recent years that obesity can be a risk factor for colorectal cancer, as well as for cardiovascular disease and metabolic disorders. Adipocytokines originate in visceral adipose tissue. The core pathogenesis of metabolic syndrome, has been found to be associated with colorectal carcinogenesis. The relevance of this factor is observed more strongly in males than in females. Weight loss and exercise may help prevent colorectal cancer.
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