| Theme | Diagnosis and Treatment of Lower Gastrointestinal Tract Submucosal Tumors | |
|---|---|---|
| Title | Diagnosis of Lower Gastrointestinal Tract GIST with Endoscopic-ultrasonographic Fine Needle Aspiration Biopsies | |
| Publish Date | 2012/07 | |
| Author | Yasumasa Niwa | Department of Endoscopy and Gastroenterology, Aichi Cancer Center Hospital |
| Author | Yoshikuni Nagashio | Department of Endoscopy and Gastroenterology, Aichi Cancer Center Hospital / Department of Gastroenterology, Aichi Cancer Center Hospital |
| Author | Kazuo Hara | Department of Gastroenterology, Aichi Cancer Center Hospital |
| Author | Masahiro Tajika | Department of Endoscopy and Gastroenterology, Aichi Cancer Center Hospital |
| Author | Yasushi Yatabe | Department of Pathology and Molecular Diagnosis, Aichi Cancer Center Hospital |
| Author | Kenji Yamao | Department of Gastroenterology, Aichi Cancer Center Hospital |
| [ Summary ] | GIST in the lower gastrointestinal tract exhibits SMT and sometimes develops in the rectum. GIST may be recognized with barium enama X-rays, colonoscopies, CTs, MRIs, or PET scans and so on. However, we can not often obtain a histological diagnosis of SMT. We can make a differential diagnosis between SMT and extracolonic compression. In addition EUS-FNA is very useful for the histological diagnosis of GIST. The primary treatment of GIST is complete surgical resection of the tumor. In cases with large tumors careful neoadjuvant therapy with imatinib should be considered as a component of strategies for GIST treatment in order to preserve anal function. | |