Clinical Gastroenterology Vol.27 No.6(4-1)

Theme More Comfortable Endoscopy -- Transnasal Endoscopy and Capsule Endoscopy
Title Transnasal and Transoral Endoscopies
Publish Date 2012/06
Author Hiroya Nakata Nakata Medical Clinic
Author Shotaro Enomoto 2nd Department of Internal Medicine, Wakayama Medical University
Author Mikitaka Iguchi 2nd Department of Internal Medicine, Wakayama Medical University
Author Hideyuki Tamai 2nd Department of Internal Medicine, Wakayama Medical University
Author Jun Kato 2nd Department of Internal Medicine, Wakayama Medical University
Author Masao Ichinose 2nd Department of Internal Medicine, Wakayama Medical University
[ Summary ] Transnasal esophagogastroduodenoscopy (EGD) is considered suitable for screening examinations because it is safer and easier to employ than transoral EGD. However, there are many problems with transnasal EGD, including image resolution and poor lighting due to the small caliber of the instruments used. We compared the screening performance of transnasal to transoral EGD. The transnasal EGD group included 1,280 subjects and the detection rate for gastric mucosal neoplasias was 1.64 % (21/1,280). The transoral EGD group included 1,707 subjects and the detection rate was 1.87 % (32/1,707), indicating no significant difference between the two groups. However, the detection rate for transoral EGD (0.79 %) was significantly higher in the screening group of subjects without gastric atrophy than that for the transnasal EGD group (0.13 %). The transoral EGD was better in terms of detecting neoplasias in subjects with H. pylori-related non-atrophic gastritis. The detection rate in the standard EGD group (3.11 %) was significantly higher than that in the transnasal EGD group (0.53 %). These results indicate that the diagnostic performance of transnasal endoscopes is suboptimal for cancer screening, especially in groups of subjects with H. pylori-related non-atrophic gastritis.
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