| Theme | Treatment for Portal Hypertension : Update | |
|---|---|---|
| Title | Partial Splenic Embolization | |
| Publish Date | 2012/02 | |
| Author | Hiroshi Yoshida | Department of Surgery, Nippon Medical School Tamanagayama Hospital |
| Author | Yasuhiro Mamada | Department of Surgery, Nippon Medical School |
| Author | Nobuhiko Taniai | Department of Surgery, Nippon Medical School |
| Author | Masato Yoshioka | Department of Surgery, Nippon Medical School |
| Author | Atsushi Hirakata | Department of Surgery, Nippon Medical School Tamanagayama Hospital |
| Author | Eiji Uchida | Department of Surgery, Nippon Medical School |
| [ Summary ] | Partial splenic embolization (PSE) is a non-surgical procedure developed to treat hypersplenism due to hepatic disease and thus avoid the disadvantages of splenectomy. Contraindications for PSE include secondary splenomegaly and hypersplenism in patients with terminal-stage underlying diseases.；Pyrexia or severe infections may be associated with a high risk of splenic abscess after PSE. A femoral artery approach is used for selective catheterization of the splenic artery. Generally, the catheter tip is placed as distally as possible in an intrasplenic artery. After injection of antibiotics and steroids, embolization is achieved by injecting 2-mm gelatin sponge cubes suspended in a saline solution containing antibiotics. Complications from PSE include daily intermittent fever, abdominal pain, nausea and vomiting, abdominal fullness, appetite loss, and postembolization syndrome. Decreased portal-vein flow and a rapid increase in platelet counts after excessive embolization may cause portal-vein or splenic-vein thrombosis. PSE is beneficial for patients with portal hypertension. |
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