| Theme | Treatment for Portal Hypertension : Update | |
|---|---|---|
| Title | Endoscopic Therapy with Cyanoacrylate for Gastric Varices | |
| Publish Date | 2012/02 | |
| Author | Takuto Hikichi | Department of Endoscopy, Fukushima Medical University Hospital |
| Author | Katsutoshi Obara | Department of Endoscopy, Fukushima Medical University Hospital |
| Author | Atsushi Irisawa | Department of Gastroenterology, Preparatory Office for Aizu Medical Center, Fukushima Medical University |
| Author | Tadayuki Takagi | Department of Gastroenterology and Rheumatology, Fukushima Medical University |
| Author | Masaki Sato | Department of Gastroenterology and Rheumatology, Fukushima Medical University |
| Author | Hiromasa Ohira | Department of Gastroenterology and Rheumatology, Fukushima Medical University |
| [ Summary ] | Rupture of gastric varices (GV) is often life-threatening because of massive bleeding. After the introduction of cyanoacrylate (CA), it become accepted that endoscopic therapy using CA is the first-line choice for treating GV bleeding. When endoscopic therapy is chosen as an additional treatment after initial hemostasis, CA/ethanolamine oleate (EO) combined therapy is useful. In CA/EO combined therapy, it is possible to obstruct not only GV but also inflow veins. Because large bulky GV and GV with red-color signs and/or erosion exhibit a high risk of bleeding, preventive treatments should be implemented using CA/EO combined therapy. This treatment is also useful in high risk GV cases. However, we must understand portal hemodynamics to perform appropriate endoscopic procedures with optimum CA concentrations. |
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