| Theme | Gastrointestinal Lymphoma -- Recent Advances in the Diagnosis and Management | |
|---|---|---|
| Title | Diagnosis and Treatment of Gastrointestinal Lymphoma | |
| Publish Date | 2012/12 | |
| Author | Shunichi Yanai | Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University |
| Author | Shotaro Nakamura | Center for Advanced Medical Innovation, Kyushu University |
| Author | Takayuki Matsumoto | Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University |
| [ Summary ] | Current diagnosis and treatment methods for gastrointestinal lymphoma are reviewed. Primary gastrointestinal lymphoma accounts for 30-50 % of all extranodal lymphomas, comprising only 1-10 % of all gastrointestinal malignancies. The most frequent histologic type is MALT lymphoma, followed by diffuse large-B-cell lymphoma. In addition, the incidence of intestinal follicular lymphoma is increasingly observed. Balloon-assisted endoscopy and capsule endoscopy are essential tools for the evaluation of small bowel lymphoma. Treatment modalities for gastrointestinal lymphomas include watch and wait, antibiotics, radiotherapy, chemotherapy, surgical resection and rituximab immunotherapy. Optimal therapeutic strategies should be determined based on the involved site, histologic type and clinical stage. It should be noted that accurate pretreatment diagnosis of the disease is most important | |