Clinical Gastroenterology Vol.27 No.1(6)

Theme Current Therapy of IBD
Title Optimization of Apheresis for Ulcerative Colitis and Crohn's Disease
Publish Date 2012/01
Author Yoko Yokoyama Division of Lower Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine
Author Ken Fukunaga Division of Lower Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine
Author Takayuki Matsumoto Division of Lower Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine
[ Summary ] There have been recent advancements in therapies for inflammatory bowel disease (IBD). GMA was established as a treatment for refractory Crohn's disease (CD) patients in 2009. Intensive treatment with CAP was accepted for UC patients in 2010. We demonstrated that UC out-patients withmoderate activity are good candidates for weekly LCAP. A close correlation between UC duration and GMA response has been proven retrospectively. We have also used weekly GMA to treat refractory CD, especially biologic-refractory conditions. CAP is the original Japanese adjunct therapy for refractory IBD. To provide optimal care we must prescribe the best means to reinforce clinical efficiency for eachform of CAP.
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